Holliston is a New England town in Middlesex County, Massachusetts, United States in the Greater Boston area. The population was 13,547 at the 2010 census, and in 2016, the population was 14,556. It is located in MetroWest, a Massachusetts region that is west of Boston. Holliston is the only town in Middlesex County that borders both Norfolk and Worcester counties. At the time of the earliest European settlements, where Holliston exists now was part of the territory of the Awassamog family of Natick (the first Nipmuc Praying Town), who also held authority over land near Waushakum Pond at Framingham and land near Annamasset at Mendon.
In 1701, a large tract of land that included the west half of Holliston, eastern Milford and parts of Hopkinton and Ashland was given to the local Nipmucs in a land exchange with Sherborn. Their ownership of the tract was brief, as settlers purchased tracts of land there until all traces of Nipmuc presence disappeared. The Nipmuc village of Mucksquit (translation – “place of much grass”), located on the shore of Wennakeening (translation – “smile of the great spirit”) was near the site of the Morse family farm, today known as Lake Winthrop. The Morses, Sheffields, Marshalls and Bullards and many others followed Pout Lane (an old Native American foot-path, now partly modern day Rte 16 and Highland St., respectively) out to the new territory and settled along the path, thus forming a cluster of farms that would eventually become Holliston.
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